| Image |
Caption |
|
| SC1000 |
Close
up of Transgenic plant callus Nicotiana tabacum
growing in nutrient agar. |
| SC1001 |
Ultra
violet visualisation of size fractionated DNA. |
| SC1002 |
Synechocystis
6803 colony, growth difference caused by introduction
of gene wild type. Photo courtesy of Dr Steve Mayes |
| SC1003 |
Protoplasts
isolated from the tobacco plant Nicotiana tabacum,
these are suitable for the study of molecular architecture
in plant cells. |
| SC1004 |
MDCK
or Canine Kidney Epithelial Cells were derived from a
kidney of an apparently normal adult female cocker spaniel
in September 1958 by S. H. Madin and N. B. Darby. The
MDCK cell line has been serially passaged since then and
has become an invaluable research tool. |
| SC1005 |
Germline
transformation of Anopheles stephensi mosquitos,
a vector of human malaria, by using the Minos transposable
element from Drosophila hydei marked with
an enhanced green fluorescent protein (EGFP) as selectable
marker.
The availability of the gene transfer technology developed
in Professor Andrea Crisanti laboratory offers a powerful
tool to investigate the role of mosquito molecules involved
in parasite-host cell interactions and opens a wide range
of applications to explore the genome of these important
disease vectors. copyright WHO/TDR/Stammers. |
| SC1006 |
Using a transposon based transformation
technique this Anopheles stephensi adult
has been genetically manipulated to express enhanced green
fluorescence protein (EGFP). The transgenes have been
stably integrated into the genome which produces a strong
fluorescence in nerve tissue especially the photoreceptor
cells of the eyes.
|
| SC1007 |
Genetically
modified mosquito larvae showing strong fluorescence of
their nervous system. Marker genes which express enhanced
green fluorescence protein (EGFP) have been integrated
into the mosquitos genome.
|
| SC1008 |
Head
of an adult mosquito Anopheles stephensi
which has been genetically manipulated in order to express
a fluorescent marker. Expression in the photoreceptors
of the eyes allows the signal to be seen in animals which
do not have a transparent cuticle.
|
| SC1009 |
LIVE
Plasmodium berghei taken from mosquito
midgut showing 3 fully developed ookinetes and 2 unfertilised
female gametes. All are genetically modifed to express
Green Fluorescence Protein, and photographed using a fluorescence
microscope and GFP filter settings. P. berghei belongs
to a group of four Plasmodium species that infect murine
rodents from Central Africa. These species are P.
vinckei, P.chabaudi, P. yoelii and P. berghei.
Females are spherical and transform to elongated ookinete
stages within 20hours after fertilisation. The bright
areas in the centre of the ookinetes are the remains of
digested haemazoin pigment granules from when the females
were developing inside their host's red blood cells. The
ookinetes travel through the gut wall of their mosquito
hosts and form cysts on the outside, which then produce
the parasite stages that can infect new hosts.
|
| Image |
Caption |
|
| SC3000 |
Anopheles
stephensi,
photographed at the London School. |
| SC3001 |
Heligosomoides
polygyrus, male and female worms. |
| SC3002 |
Anopheles
stephensi,
photographed at the London School. |
| SC3003 |
Aedes
aegypti. |
| SC3004 |
Fasciola
hepatica, dark field. |
| SC3005 |
Rhodnius
prolixus, a triatomine bug, feeding on
human blood. |
| SC3006 |
Trypanosoma
brucei, tryptomastigote stage in thin blood
film. |
| SC3007 |
Echinococcus
granulosus hydatid cysts in Horse liver. |
| SC3008 |
Lutzomyia
longipalpis (Diptera: Psychodidae) blood feeding
on human host. |
| SC3009 |
Cimex
lectularius The Bedbug, blood feeding on
human host. |
| SC3010 |
Ornithodorous
moubata or
the African Tampan, a soft tick engorged with blood after
inflicting a painful bite on a human host. |
| |
|
| SC3011 |
Echinococcus
granulosus protoscolex containing calcareous
corpuscles and rostellar hooks. Phase contrast photomicrograph
magn.x250 |
| SC3012 |
Schistosoma
haematobium
adult male enclosing female as found in mesenteric vein.
magn.x10 |
| SC3013 |
Schistosoma
haematobium cercarial stage magn.x500 |
| SC3014 |
Schistosoma
haematobium miracidium swimming freely.
Flash photomicrograph using differential interference
contrast at sensitive grey setting. Length approximately
50 micrometres,sample courtesy Dr Alison Agnew. |
| SC3015 |
Schistosoma
haematobium
spined egg capsule is deposited by female worm in mesenteric
venule, some will escape to exterior of host through the
colon or bladder, others become trapped in deeper viscera
causing inflammation and fibrosis. |
| SC3016 |
Aedes
albopictus (Skuse) blood feeding on human skin
|
| SC3017 |
Trypanosoma
cruzi monaxenic
culture Differential Interference Contrast x2500 cause
of sleeping sickness. |
| SC3018 |
Dog
Roundworm or
Toxascaris leonina embryo L2 larva
within egg. Differential Interference Contrast low magnification,
egg diameter 80x67 micrometres. |
| SC3019 |
African
Black Fly or Simulium damnosum blood feeding
on a human host at Daboese, Ghana. The tarsal claws
on the first pair of legs are upturned, possibly this
helps to avoid alerting the human host to its presence.
Human infection by the nematode Onchocerca volvulus
is caused by the transmission of the nematode
through the intermediate host Simulium damnosum,
the resulting human disease is called African River
Blindness or Onchocerciasis.
|
| SC3020 |
Black
Fly Simulium damnosum the
main vectors of Onchocerciasis. This is caused by the
nematode Onchocerca volvulus which is ingested
when the fly takes a blood meal from a human host. Various
stages of microfilariae develop within the fly until the
L3 larval stage migrates to the head and mouth for future
infection of the next human host. |
| SC3021 |
Simulium
damnosum pupae from Boti Falls, Ghana |
| SC3022 |
Anopheles
stephensi |
| SC3023 |
Eggs
of Toxascaris leonina or Dog Roundworm
|
| SC3024 |
"The
Malaria mosquito" Anopheles gambiae
is the main vector of malaria in Africa especially Plasmodium
falciparum.This parasitic disease infects from
300 to 500 million persons per year in the world, and
kills more than a million and a half each year, mainly
African children. |
| SC3025 |
Anopheles
gambiae taking
a blood meal, mosquitos are nectar feeders but
before laying eggs the female requires iron and protein
from blood.The mouthparts are a pair of needle like tubes,
and with each bite, one tube sends anti-coagulants and
other chemicals into the hosts bloodstream so that blood
flows freely into her stomach |
| SC3026 |
Trichuris
trichiura from
the human caecum |
| SC3027 |
Anopheles
stephensi taking a human blood meal, Ashworth
laboratories, Edinburgh |
| SC3028 |
Anopheles
stephensi Ashworth laboratories, Edinburgh |
| SC3029 |
The
mosquito Anopheles stephensi lives in urban
areas and the larvae are found in a wide variety of artifical
containers, cisterns, wells, tubs and fountains. In the
wild they are found in stream pools, stream margins, seepages,
irrigation channels and springs. Females avidly bite man.
|
